教育经历:
(1) 2014-09 至 2021-09,吉大林学,预防兽医学,博士
(2) 2005-09 至 2008-07,东北农业大学,预防兽医学,硕士
(3)1997-09 至 2001-07,东北农业大学,动物药学,学士
科研与学术工作经历(博士后工作经历除外):
(1) 2021-09 至 今,东北农业大学,350vip浦京集团·(中国)有限公司,副教授
(2) 2014-09 至 2021-09,东北农业大学, 350vip浦京集团·(中国)有限公司,高级实验师
(3) 2009-01 至 2014-09,东北农业大学,350vip浦京集团·(中国)有限公司,实验师
(4) 2001-07 至 2005-05, 哈药集团生物疫苗有限公司,诊断制剂车间
近五年主持科研项目/课题:
(1) 农业农村部、财政部, 现代农业产业技术体系, CARS-36,国家产业技术体系——奶牛病毒性传染病防 控岗位科学家, 2021-01 至 2025-12,在研,主持
(2) 黑龙江省科学技术厅,黑龙江省奶牛协同创新体系岗位科学家,2023-01至2026-01,在研,主持
(3) 黑龙江省科学技术厅, 黑龙江省自然科学基金,LH2023C022,BPIV3经NF-κB/STAT3负调控抗病毒应答的分子机制, 2023-07 至 2026-07,在研,主持
论文
1.Dai H, Wang Y, Fan Z, Guo Y, Chen J, Meng Y, Tong X, Gao M, Wang J. Bovine cyclic GMP-AMP synthase recognizes exogenous double-stranded DNA and activates the STING-depended interferon β production pathway. Developmental & Comparative Immunology 2023, 139: 104567.
2.An R, Zhang R, Guo Y, Geng J, Si M, Wang S, Gao M, Wang J. Biological Activity of Optimized Codon Bovine Type III Interferon Expressed in Pichia pastoris. VIRUSES-BASEL 2023, 15(5): 1101.
3.Qu Z, Li M, An R, Dai H, Yu Y, Li C, Cao C, Meng Y, Wang J, Gao M. Self-assembled BPIV3 nanoparticles can induce comprehensive immune responses and protection against BPIV3 challenge by inducing dendritic cell maturation in mice. VET MICROBIOL 2022, 268: 109415.
4.Dai H, Wu J, Yang H, Guo Y, Di H, Gao M, Wang J. Construction of BHV-1 UL41 Defective Virus Using the CRISPR/Cas9 System and Analysis of Viral Replication Properties. FRONT CELL INFECT MI 2022, 12: 942987.
5.An R, Gao M, Meng Y, Tong X, Chen J, Wang J. Infective mastitis due to bovine‐associatedStreptococcus dysgalactiae contributes to clinical persistent presentation in a murine mastitis model. VET MED SCI 2021, 7(5): 1600-1610.
6.Guo Y, Song Z, Cheng X, Wang Y, Luo X, An R, Wang J, Gao M. Molecular and functional characterization of ovis aries IFN-epsilon. MOL IMMUNOL 2020, 119: 1-7.
7.Guo Y, Song Z, Li C, Yu Y, Dai H, Luo X, Wang Y, Wang J, Gao M. A Novel Type-I Interferon Family, Bovine Interferon-Chi, Is Involved in Positive-Feedback Regulation of Interferon Production. FRONT IMMUNOL 2020, 11: 528854.
8.Qu Z, Guo Y, Li M, Cao C, Wang J, Gao M. Recombinant ferritin nanoparticles can induce dendritic cell maturation through TLR4/NF-κB pathway. BIOTECHNOL LETT 2020, 42(12): 2489-2500.
9.Qu Z, Li M, Guo Y, Liu Y, Wang J, Gao M. Expression, purification, and characterisation of recombinant ferritin in insect cells using the baculovirus expression system. BIOTECHNOL LETT 2020, 42(1): 57-65.
10.Gao M, Guo Y, Luo X, Du J, Wang Y, Cao C, Wang J, Han W. Design, biological activity and signaling pathway of bovine consensus omega interferon expressed in Pichia pastoris. MOL IMMUNOL 2019, 106: 46-52.
11.Gao M, Guo Y, Du J, Song Z, Luo X, Wang J, Han W. Evolutional conservation of molecular structure and antiviral function of a type I interferon, IFN-kappa, in poultry. Developmental & Comparative Immunology 2018, 89: 44-53.
12.Gao M, Liu Y, Guo Y, Wang Y, Dai H, Song Z, Wang J, Han W. Identification and characterization of a rabbit novel IFN-α unlocated in genome. Developmental & Comparative Immunology 2018, 78: 91-99.
专利:
1.高明春; 戴海越; 郭永丽; 王君伟;陈佳奇;孟野;佟欣;吴佳楠;杨鸿术;安冉;一种牛疱疹病毒1型UL41缺失毒株及其获取方法, 2023-08-11,中国,CN202111446165.8
2.高明春; 路紫微; 王祎潇; 郭永丽;王君伟;吴佳楠; 侯亚娟;细胞膜穿透肽与牛SOCS3的融合肽及其在促进BPIV3增殖中的应用, 2023-7-6,中国, CN202310826724.0
3.高明春; 郭永丽; 孙进华;王君伟;罗修鑫;曹翀;刘莹;安东;周萍萍;重组牛共有ω-干扰素及其应用, 2018-12-28,中国, ZL105131103B(授权)
4.高明春; 张润祥; 刘洪贵; 孙旭燕; 王君伟;马波;崔子寅;重组牛alpha干扰素及其应用,2016-6-29,中国, CN201310381419.1(授权)