黑龙江省D类人才

1.黑龙江省畜牧兽医学会寄生虫病学分会第五届理事会理事长

2.中国畜牧兽医学会兽医寄生虫学分会理事

1.旋毛虫丝氨酸蛋白酶抑制剂在虫体与宿主相互作用中的机制研究，31372427，国家自然科学基金面上项目，2014-01--2017-12

2.丝氨酸蛋白酶抑制剂在旋毛虫侵入宿主肠上皮细胞过程中的作用研究，20132325110002，教育部博导基金，2014-01--2016-12

3.旋毛虫丝氨酸蛋白酶抑制剂在抑制宿主免疫反应中的作用机制研究，C2016030，黑龙江省基金面上项目，2016-07--2019-07

4.严重危害畜禽生产寄生虫病的诊断、检测与防控新技术研究----反刍动物肝片吸虫病早期诊断与控制技术研究，2017YFD0501202-2，国家重点研发计划子课题，2017-07--2020-12

5.旋毛虫丝氨酸蛋白酶抑制剂在虫体入侵宿主过程中对肠道炎症反应的调控机制研究，SKLVEB2019KFKT011，家畜疫病病原生物学国家重点实验室开发基金课题，2019-12---2021-11

6.利用秀丽隐杆线虫研究捻转血矛线虫疫苗候选抗原蛋白的生物学功能，C200929，黑龙江省基金面上项目，2010-01--2012-12

7.旋毛虫实时荧光PCR快速检测试剂盒的研究，1153Lz04，黑龙江省教育厅重点项目，2008-01--2010-12

1.分子寄生虫学，博士研究生，48学时

2.预防兽医学学科前沿讲座与研讨，博士研究生，16学时

3.兽医体系与管理，专业博士研究生，32学时

4.兽医学进展专题讲座，专业博士研究生，16学时

5.兽医寄生虫病学，硕士研究生，48学时

6.蜘蛛昆虫学实验技术，硕士研究生，64学时

7.兽医法律法规，专业学位硕士研究生，32学时

8.家畜寄生虫与寄生虫病学，本科生，72学时

9.传染病综合诊治大实验，本科生，40学时

1.Jingbo Zhen; Lihao Lin; Zhixin Li; Feng Sun; Yang Han; Qiankun Li; Yuqi Yang; Xueting Liu; Junchen Yu; Qi Zhang;Yixin Lu*;CaixiaH.Regulatory effects of Trichinella spiralis serpin-type serine protease inhibitor on endoplasmic reticulum stress and oxidative stress in host intestinal epithelial cells.Veterinary Research,55, 78 (2024).

2.Jing-Bo Zhen; Rui-Biao Wang; Yu-Heng Zhang; Feng Sun; Li-Hao Lin; Zhi-Xin Li; Yang Han; Yi-Xin Lu*.Effects of Trichinella spiralis and its serine protease inhibitors on autophagy of host small intestinal cells.Infection and Immunity,24 October 2023Vol. 91, No. 11

3.Ruibiao Wang; Lihao Lin; Yang Han; Zhixin Li; Jingbo Zhen; Yuheng Zhang; Feng Sun; Yixin Lu*.Exosome-delivered miR-153 from Trichinella spiralis promotes apoptosis of intestinal epithelial cells by downregulating Bcl2.Veterinary Research,54, 52 (2023).

4.JingBo Zhen, JinPeng Zhang, Feng Sun, LiHao Lin, YuHeng Zhang, RuiBiao Wang,Yang Han, ZhiXin Li, YiXin Lu*.Intervention effects of Trichinella spiralis excretory-secretory antigens on allergic asthma in mice.International Immunopharmacology,Volume119,June2023,pp.110101

5.Ruibiao Wang, Yuheng Zhang, Jingbo Zhen, Jinpeng Zhang, Zixuan Pang, Xuewei Song, Lihao Lin,Feng Sun and Yixin Lu*.Effects of exosomes derived from Trichinella spiralis infective larvae on intestinal epithelial barrier function.Veterinary Research, (2022) 53:87.

6.Jingyun Xu, Zixuan Pang, Jinpeng Zhang, Shuang Xia, Ruibiao Wang, Yuheng Zhang, Jingbo Zhen,Xuewei Song, Lihao Lin, Feng Sun, Xinxin Xuan and Yixin Lu*.Regulatory effects of Trichinella spiralis and a serine protease inhibitor on the endoplasmic reticulum stress response of intestinal epithelial cells.Veterinary Research, (2022) 53:18.

7.Nana Yi，Pengcheng Yu，Lijia Wu，Zhaokun Liu，Jingzhe Guan，Chang Liu，Mingxu Liu，Yixin Lu*.RNAimediated silencing of Trichinella spiralis serpintype serine protease inhibitors results in a reduction in larval infectivity. Veterinary Research,(2020) 51:139.

8.Yang Zou, Wen-Bin Zheng, Jun-Jun He, Hany M. Elsheikha, Xing-Quan Zhu* and Yi-Xin Lu*.Toxocara canis Differentially Affects Hepatic MicroRNA Expression in Beagle Dogs at Different Stages of Infection. Frontiers in Veterinary Science,November 2020 | Volume 7 | Article 587273

9.Jingyun Xu , Lijia Wu , Yichun Sun, Yating Wei, Lushan Zheng, Jinpeng Zhang, Zixuan Pang, Ying Yang,Yixin Lu*,Proteomics and bioinformatics analysis of Fasciola hepatica somatic proteome in different growth phases. Parasitology Research, (2020) 119:2837—2850 .

10.Jingyun Xu，Lijia Wu，Pengcheng Yu，Yichun Sun & Yixin Lu*.Effect of T. spiralis Serine protease inhibitors on TNBS-induced experimental colitis mediated by Macrophages. Scientific Reports,(2020) 10:3147.

11.Li Li, Zhe Hu, Jinhui Sun, Kui Guo, Xiaoyu Chu, Xiaojun Wang, Yixin Lu*.Development of an EvaGreen-based real-time PCR assay for detection of Aleutian mink disease virus. Journal of Virological Methods, 275 (2020) 113751

12.Jingyun Xu, Pengcheng Yu, Lijia Wu, Mingxu Liu & Yixin Lu*. Regulatory effect of two Trichinella spiralis serine protease inhibitors on the host’s immune system. scientific reports,(2019) 9:17045

13.Jingyun Xu, Mingxu Liu, Pengcheng Yu, Lijia Wu, Yixin Lu*. Effect of recombinant Trichinella spiralis cysteine proteinase inhibitor on TNBS-inducedexperimental inflammatory bowel disease in mice. International Immunopharmacology.66（2019）28-40.

14.Jingyun Xu, Pengcheng Yu, Lijia Wu, Mingxu Liu, Yixin Lu*.Effect of Trichinella spiralis intervention on TNBS-induced experimental colitis in mice.Immunobiology,224（2019）147-153

15.J. Xu, L. Wu, P. Yu, M. Liu,Y. Lu*. Effect of two recombinant Trichinella spiralis serine protease inhibitors on TNBS-induced experimental colitis of mice. Clinical and Experimental Immunology, 2018 Dec;194(3):400-413.

16.Qiao-Cheng Chang, Yang Hu, Ming-Hao Zeng, Jun-Feng Gao, Ye Li, Yi-Xin Lu* and Chun-Ren Wang. The complete mitochondrial genome of Fimbriaria fasciolaris (Hymenolepididae). MITOCHONDRIAL DNA PART B Resources,2018, VOL. 4, NO. 1, 120–121

17.Zhaoxia Zhang，Yixian Mao，Da Li，Yvhan Zhang，Wei Li，Honglin Jia，Jun Zheng，Li Li，Yixin Lu*.High-level expression and characterization of two serine protease inhibitors from Trichinella spiralis.Veterinary Parasitology,2016,219：34-39

18.Lu, Yixin(#)，Han, Caixia，Yang, Jinyu，Li, Xiaoyun，Song, Mingxin，Molecular identification of three Trichinella isolates from Heilongjiang Province, People';s Republic of China.Experimental Parasitology,2011,129（3）:299-302